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Breakthrough in GPCR Crystallography and its Impact on Computer-Aided Drug Design
Complete Nucleotide Sequence and Organization of the Atrazine Catabolic Plasmid pADP-1 from Pseudomonas sp. Strain ADP

Identification of a Different Agonist-Binding Site and Activation Mechanism of the Human P2Y(1) Receptor
Mechanistic insights into multiple-step transport of mitochondrial ADP/ATP carrier

Apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers is lower in water enriched in oxygen by electrolysis than injection
Exhaustion of Skeletal Muscle Fibers Within Seconds: Incorporating Phosphate Kinetics Into a Hill-Type Model

The Father, Son and Cholix Toxin: The Third Member of the DT Group Mono-ADP-Ribosyltransferase Toxin Family
Mitochondrial Energetics, pH Regulation, and Ion Dynamics: A Computational-Experimental Approach

Understanding the Phosphorylation Mechanism by Using Quantum Chemical Calculations and Molecular Dynamics Simulations
Actin filament severing by cofilin is more important for assembly than constriction of the cytokinetic contractile ring

In Silico Screening Identifies a Novel Potential PARP1 Inhibitor Targeting Synthetic Lethality in Cancer Treatment
Mathematical Simulation of Muscle Cross-Bridge Cycle and Force-Velocity Relationship

Use of Protein Kinase Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors
Ligand Selectivity between the ADP-Ribosylating Toxins: An Inverse-Docking Study for Multitarget Drug Discovery

A Kinetic Model Describing the Processivity of Myosin-V
Topographic Studies of the GroEL-GroES Chaperonin Complex by Chemical Cross-linking Using Diformyl Ethynylbenzene: THE POWER OF HIGH RESOLUTION ELECTRON TRANSFER DISSOCIATION FOR DETERMINATION OF BOTH PEPTIDE SEQUENCES AND THEIR ATTACHMENT SITES

Identification of potential microRNA–target pairs associated with osteopetrosis by deep sequencing, iTRAQ proteomics and bioinformatics
Modeling Cardiac Action Potential Shortening Driven by Oxidative Stress-Induced Mitochondrial Oscillations in Guinea Pig Cardiomyocytes

A thermodynamically consistent model of the post-translational Kai circadian clock
Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial

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