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Actin filament severing by cofilin is more important for assembly than constriction of the cytokinetic contractile ring
We created two new mutants of fission yeast cofilin to investigate why cytokinesis in many organisms depends on this small actin-binding protein. These mutant cofilins bound actin monomers normally, but bound and severed ADP-actin filaments much slower than wild-type cofilin. Cells depending on muta...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Rockefeller University Press
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3206353/ https://ncbi.nlm.nih.gov/pubmed/22024167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201103067 |
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