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Actin filament severing by cofilin is more important for assembly than constriction of the cytokinetic contractile ring

We created two new mutants of fission yeast cofilin to investigate why cytokinesis in many organisms depends on this small actin-binding protein. These mutant cofilins bound actin monomers normally, but bound and severed ADP-actin filaments much slower than wild-type cofilin. Cells depending on muta...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Qian, Pollard, Thomas D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206353/
https://ncbi.nlm.nih.gov/pubmed/22024167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201103067
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