Resultados da pesquisa - (( e nat (comp OR com) a newly ) OR ((( 3 natl co2 case new ) OR ( _ daily comecaram a non ))))

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comp » como (Expandir a Pesquisa), come (Expandir a Pesquisa)

1

OS09.8 Randomized placebo-controlled trial of autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma

OS09.8 Randomized placebo-controlled trial of autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma

Por Muragaki, Y., Maruyama, T., Ishikawa, E., Nitta, M., Ikuta, S., Yamamoto, T., Tsuboi, K., Matsumura, A., Nakamura, H., Kuroda, J., Abe, T., Abe, T.
Publicado no Neuro Oncol (2017)

“... randomly assigned 1:1 to receive AFTV (2 courses; 3 times, once a week) + RT/TMZ or Pla + RT/TMZ until...”
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2

OS12.6 Intracranial GBM PDX Mutations Induced by Temozolomide Treatment

OS12.6 Intracranial GBM PDX Mutations Induced by Temozolomide Treatment

Por James, C, Horbinski, C, Bartom, E, Burdett, K, Scholtens, D, Ahmed, A
Publicado no Neuro Oncol (2019)

“... with newly diagnosed glioblastoma (GBM). Nearly all GBM recur following TMZ treatment...”
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3

Immune complex relay by subcapsular sinus macrophages and non-cognate B cells drives antibody affinity maturation

Immune complex relay by subcapsular sinus macrophages and non-cognate B cells drives antibody affinity maturation

Por Phan, Tri Giang, Green, Jesse A., Gray, Elizabeth E., Xu, Ying, Cyster, Jason G.
Publicado em 2009

“... show SCS macrophage development depended on lymphotoxin-α1β2 and the cells had low lysosomal enzyme...”
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4

Relapse specific mutations in NT5C2 in childhood acute lymphoblastic leukemia

Relapse specific mutations in NT5C2 in childhood acute lymphoblastic leukemia

Por Meyer, Julia A., Wang, Jinhua, Hogan, Laura E., Yang, Jun J., Dandekar, Smita, Patel, Jay P., Tang, Zuojian, Zumbo, Paul, Li, Sheng, Zavadil, Jiri, Levine, Ross L., Cardozo, Timothy, Hunger, Stephen P., Raetz, Elizabeth A., Evans, William E., Morrison, Debra J., Mason, Christopher E., Carroll, William L.
Publicado em 2013

“... identified 20 newly acquired novel non-synonymous mutations not present at initial diagnosis, of which two...”
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5

The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability

The RNA-binding protein SFPQ orchestrates an RNA regulon to promote axon viability

Por Cosker, Katharina E, Fenstermacher, Sara J, Pazyra-Murphy, Maria F, Elliott, Hunter L, Segal, Rosalind A
Publicado no Nat Neurosci (2016)

“... related mRNAs essential for axon survival. Notably SFPQ is required for co-assembly of laminb2 and bclw...”
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6

High-affinity free ubiquitin sensors for quantifying ubiquitin homeostasis and deubiquitination

High-affinity free ubiquitin sensors for quantifying ubiquitin homeostasis and deubiquitination

Por Choi, Yun-Seok, Bollinger, Sarah A., Prada, Luisa F., Scavone, Francesco, Yao, Tingting, Cohen, Robert E.
Publicado no Nat Methods (2019)

“..., and yet the dynamics and regulation of even free (i.e., unconjugated) Ub are poorly understood. A major...”
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7

Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesions

Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesions

Por Ordonez, Alvaro A., Wang, Hechuan, Magombedze, Gesham, Ruiz-Bedoya, Camilo A., Srivastava, Shashikant, Chen, Allen, Tucker, Elizabeth W., Urbanowski, Michael E., Pieterse, Lisa, Cardozo, E. Fabian, Lodge, Martin A., Shah, Maunank R., Holt, Daniel P., Mathews, William B., Dannals, Robert F., Gobburu, Jogarao V. S., Peloquin, Charles A., Rowe, Steven P., Gumbo, Tawanda, Ivaturi, Vijay D., Jain, Sanjay K.
Publicado no Nat Med (2020)

“... and shorten TB treatments(2). In this study, we applied a new tool to perform unbiased, noninvasive...”
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8

Worldwide distribution of <it>NAT2 </it>diversity: Implications for <it>NAT2 </it>evolutionary history

Worldwide distribution of <it>NAT2 </it>diversity: Implications for <it>NAT2 </it>evolutionary history

Por Gérard Nathalie, Darlu Pierre, Langaney André, Sabbagh Audrey, Krishnamoorthy Rajagopal, Poloni Estella S
Publicado em 2008-02-01

“...<p>Abstract</p> <p>Background</p> <p>The N-acetyltransferase 2 (<it>NAT2</it>) gene plays a crucial...”
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9

An In Vitro Translation, Selection, and Amplification System for Peptide Nucleic Acids

An In Vitro Translation, Selection, and Amplification System for Peptide Nucleic Acids

Por Brudno, Yevgeny, Birnbaum, Michael E., Kleiner, Ralph E., Liu, David R.
Publicado em 2009

“... template; (ii) display of the newly translated polymer strand in a manner that allows it to adopt folded...”
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10

Mitochondrial reactive oxygen species regulate the strength of inhibitory GABA-mediated synaptic transmission

Mitochondrial reactive oxygen species regulate the strength of inhibitory GABA-mediated synaptic transmission

Por Accardi, Michael V., Daniels, Bryan A., Brown, Patricia M.G.E., Fritschy, Jean-Marc, Tyagarajan, Shiva K., Bowie, Derek
Publicado no Nat Commun (2014)

“... events with unique kinetic properties, we conclude that newly-recruited α3-containing GABA(A) receptors...”
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11

High density three-dimensional localization microscopy across large volumes

High density three-dimensional localization microscopy across large volumes

Por Legant, Wesley R., Shao, Lin, Grimm, Jonathan B., Brown, Timothy A., Milkie, Daniel E., Avants, Brian B., Lavis, Luke D., Betzig, Eric
Publicado no Nat Methods (2016)

“...Extending three-dimensional (3D) single molecule localization microscopy away from the coverslip...”
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12

Regioselective Reactions of 3,4-Pyridynes Enabled by the Aryne Distortion Model

Regioselective Reactions of 3,4-Pyridynes Enabled by the Aryne Distortion Model

Por Goetz, Adam E., Garg, Neil K.
Publicado em 2012

“...The pyridine heterocycle continues to play a vital role in the development of human medicines. More...”
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13

Heparanase is a Host Enzyme Required for Herpes Simplex Virus-1 Release from Cells

Heparanase is a Host Enzyme Required for Herpes Simplex Virus-1 Release from Cells

Por Hadigal, Satvik R., Agelidis, Alex M., Karasneh, Ghadah A., Antoine, Thessicar E., Yakoub, Abraam M., Ramani, Vishnu C., Djalilian, Ali R., Sanderson, Ralph D., Shukla, Deepak
Publicado no Nat Commun (2015)

“... can trap newly exiting viral progenies and inhibit their release. Here, we demonstrate that a HS...”
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14

Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75

Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75

Por Berndsen, Christopher E, Tsubota, Toshiaki, Lindner, Scott E, Lee, Susan, Holton, James M, Kaufman, Paul D, Keck, James L, Denu, John M
Publicado em 2008

“..., functions with the histone chaperone Asf1 to acetylate lysine K56 on histone H3 (H3K56), a modification...”
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15

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

Por Liu, Jimmy Z, Almarri, Mohamed A, Gaffney, Daniel J, Mells, George F, Jostins, Luke, Cordell, Heather J, Ducker, Samantha J, Day, Darren B, Heneghan, Michael A, Neuberger, James M., Donaldson, Peter T, Bathgate, Andrew J, Burroughs, Andrew, Davies, Mervyn H, Jones, David E, Alexander, Graeme J, Barrett, Jeffrey C, Sandford, Richard N, Anderson, Carl A
Publicado em 2012

“.... The most associated variant at 19p12 is a low-frequency non-synonymous SNP in TYK2, further implicating JAK...”
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16

Computational Design of Self-Assembling Cyclic Protein Homo-oligomers

Computational Design of Self-Assembling Cyclic Protein Homo-oligomers

Por Fallas, Jorge A., Ueda, George, Sheffler, William, Nguyen, Vanessa, McNamara, Dan E., Sankaran, Banumathi, Pereira, Jose Henrique, Parmeggiani, Fabio, Brunette, TJ, Cascio, Duilio, Yeates, Todd R., Zwart, Peter, Baker, David
Publicado no Nat Chem (2016)

“... we report a general approach to design cyclic homo-oligomers that employs a new residue pair...”
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17

Genome-wide association studies identify novel loci associated with age at menarche and age at natural menopause

Genome-wide association studies identify novel loci associated with age at menarche and age at natural menopause

Por He, Chunyan, Kraft, Peter, Chen, Constance, Buring, Julie E., Paré, Guillaume, Hankinson, Susan E., Chanock, Stephen J., Ridker, Paul M., Hunter, David J., Chasman, Daniel I.
Publicado em 2009

“... of these two traits in a total of 17,438 women from the Nurses’ Health Study (NHS, N=2,287) and the Women’s...”
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18

AdPLA ablation increases lipolysis and prevents obesity induced by high fat feeding or leptin deficiency

AdPLA ablation increases lipolysis and prevents obesity induced by high fat feeding or leptin deficiency

Por Jaworski, Kathy, Ahmadian, Maryam, Duncan, Robin E., Sarkadi-Nagy, Eszter, Varady, Krista A., Hellerstein, Marc K., Lee, Hui-Young, Samuel, Varman T., Shulman, Gerald I., Kim, Kee-Hong, de Val, Sarah, Kang, Chulho, Sul, Hei Sook
Publicado em 2009

“... identified major adipocyte phospholipase A(2), in the regulation of lipolysis and adiposity. AdPLA null mice...”
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19

Video-rate nanoscopy enabled by sCMOS camera-specific single-molecule localization algorithms

Video-rate nanoscopy enabled by sCMOS camera-specific single-molecule localization algorithms

Por Huang, Fang, Hartwich, Tobias M. P., Rivera-Molina, Felix E., Lin, Yu, Duim, Whitney C., Long, Jane J., Uchil, Pradeep D., Myers, Jordan R., Baird, Michelle A., Mothes, Walther, Davidson, Michael W., Toomre, Derek, Bewersdorf, Joerg
Publicado em 2013

“...Newly developed scientific complementary metal–oxide–semiconductor (sCMOS) cameras have...”
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20

Dynamics of the human gut microbiome in Inflammatory Bowel Disease

Dynamics of the human gut microbiome in Inflammatory Bowel Disease

Por Halfvarson, Jonas, Brislawn, Colin J., Lamendella, Regina, Vázquez-Baeza, Yoshiki, Walters, William A., Bramer, Lisa M., D’Amato, Mauro, Bonfiglio, Ferdinando, McDonald, Daniel, Gonzalez, Antonio, McClure, Erin E., Dunklebarger, Mitchell F., Knight, Rob, Jansson, Janet K.
Publicado no Nat Microbiol (2017)

“... from a newly-defined healthy plane (HP). ICD subjects deviated most from the HP, especially subjects...”
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