Heparanase is a Host Enzyme Required for Herpes Simplex Virus-1 Release from Cells

Herpesviruses exemplified by herpes simplex virus-1 (HSV-1) attach to cell surface heparan sulfate (HS) for entry into host cells. However, during a productive infection the HS moieties on parent cells can trap newly exiting viral progenies and inhibit their release. Here, we demonstrate that a HS-d...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Hadigal, Satvik R., Agelidis, Alex M., Karasneh, Ghadah A., Antoine, Thessicar E., Yakoub, Abraam M., Ramani, Vishnu C., Djalilian, Ali R., Sanderson, Ralph D., Shukla, Deepak
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413471/
https://ncbi.nlm.nih.gov/pubmed/25912399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7985
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