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An off-target effect of BX795 blocks herpes simplex virus type-1 infection of the eye
Herpes simplex virus type-1 (HSV-1) causes recurrent mucocutaneous lesions in the eye that may advance to corneal blindness. Nucleoside analogs exemplified by acyclovir (ACV) form the primary class of anti-herpetic drugs but this class suffers limitations due to the emergence of viral resistance and...
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| 出版年: | Sci Transl Med |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7540910/ https://ncbi.nlm.nih.gov/pubmed/29444978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan5861 |
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