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An off-target effect of BX795 blocks herpes simplex virus type-1 infection of the eye

Herpes simplex virus type-1 (HSV-1) causes recurrent mucocutaneous lesions in the eye that may advance to corneal blindness. Nucleoside analogs exemplified by acyclovir (ACV) form the primary class of anti-herpetic drugs but this class suffers limitations due to the emergence of viral resistance and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Transl Med
Päätekijät: Jaishankar, Dinesh, Yakoub, Abraam M., Yadavalli, Tejabhiram, Agelidis, Alex, Thakkar, Neel, Hadigal, Satvik, Ames, Joshua, Shukla, Deepak
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540910/
https://ncbi.nlm.nih.gov/pubmed/29444978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan5861
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