Novel Synthetic Toll-Like Receptor 4/MD2 Ligands Attenuate Sterile Inflammation

Por Hayashi, Tomoko, Crain, Brian, Yao, Shiyin, Caneda, Christa D., Cottam, Howard B., Chan, Michael, Corr, Maripat, Carson, Dennis A.
Publicado em 2014

Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization

Por Wang, Wei-Peng, Ho, Pui Yan, Chen, Qiu-Xia, Addepalli, Balasubrahmanyam, Limbach, Patrick A., Li, Mei-Mei, Wu, Wen-Juan, Jilek, Joseph L., Qiu, Jing-Xin, Zhang, Hong-Jian, Li, Tianhong, Wun, Theodore, White, Ralph DeVere, Lam, Kit S., Yu, Ai-Ming
Publicado no J Pharmacol Exp Ther (2015)

Medication Repurposing in Pediatric Patients: Teaching Old Drugs New Tricks

Por Rumore, Martha M.
Publicado no J Pediatr Pharmacol Ther (2016)

Niacin as a drug repositioning candidate for hyperphosphatemia management in dialysis patients

Por Shin, Sooyoung, Lee, Sukhyang
Publicado em 2014

The Fate and Function of Therapeutic Antiaddiction Monoclonal Antibodies across the Reproductive Cycle of Rats

Por Hubbard, Jonathan J., Laurenzana, Elizabeth M., Williams, D. Keith, Gentry, W. Brooks, Owens, S. Michael
Publicado em 2011

Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro

Por Neumann, Susanne, Eliseeva, Elena, Boutin, Alisa, Barnaeva, Elena, Ferrer, Marc, Southall, Noel, Kim, David, Hu, Xin, Morgan, Sarah J., Marugan, Juan J., Gershengorn, Marvin C.
Publicado no J Pharmacol Exp Ther (2018)

A Genomic DNA Reporter Screen Identifies Squalene Synthase Inhibitors That Act Cooperatively with Statins to Upregulate the Low-Density Lipoprotein Receptor

Por Kerr, Alastair G., Tam, Lawrence C. S., Hale, Ashley B., Cioroch, Milena, Douglas, Gillian, Agkatsev, Sarina, Hibbitt, Olivia, Mason, Joseph, Holt-Martyn, James, Bataille, Carole J. R., Wynne, Graham M., Channon, Keith M., Russell, Angela J., Wade-Martins, Richard
Publicado no J Pharmacol Exp Ther (2017)

Microdose-induced Drug-DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice

Por Zimmermann, Maike, Wang, Si-Si, Zhang, Hongyong, Lin, Tzu-yin, Malfatti, Michael, Haack, Kurt, Ognibene, Ted, Yang, Hongyuan, Airhart, Susan, Turteltaub, Kenneth W., Cimino, George D., Tepper, Clifford G., Drakaki, Alexandra, Chamie, Karim, de Vere White, Ralph, Pan, Chong-xian, Henderson, Paul T.
Publicado no Mol Cancer Ther (2016)

Differences in Methylphenidate Dose Response between Periadolescent and Adult Rats in the Familiar Arena-Novel Alcove Task

Por Levant, Beth, Zarcone, Troy J., Davis, Paul F., Ozias, Marlies K., Fowler, Stephen C.
Publicado em 2011

HD047703, a New Promising Anti-Diabetic Drug Candidate: In Vivo Preclinical Studies

Por Kim, SoRa, Kim, Dae Hoon, Kim, Young-Seok, Ha, Tae-Young, Yang, Jin, Park, Soo Hyun, Jeong, Kwang Won, Rhee, Jae-Keol
Publicado em 2014

Multiple-dose pharmacokinetics and pharmacodynamics of evogliptin (DA-1229), a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers

Por Gu, Namyi, Park, Min Kyu, Kim, Tae-Eun, Bahng, Mi Young, Lim, Kyoung Soo, Cho, Sang-Heon, Yoon, Seo Hyun, Cho, Joo-Youn, Jang, In-Jin, Yu, Kyung-Sang
Publicado em 2014

Pharmacologic Targeting of Bacterial β-Glucuronidase Alleviates Nonsteroidal Anti-Inflammatory Drug-Induced Enteropathy in Mice

Por LoGuidice, Amanda, Wallace, Bret D., Bendel, Lauren, Redinbo, Matthew R., Boelsterli, Urs A.
Publicado em 2012

Therapeutic Effect of Sodium Iodide Symporter Gene Therapy Combined With External Beam Radiotherapy and Targeted Drugs That Inhibit DNA Repair

Por Hingorani, Mohan, White, Christine L, Zaidi, Shane, Pandha, Hardev S, Melcher, Alan A, Bhide, Shreerang A, Nutting, Christopher M, Syrigos, Konstantinos N, Vile, Richard G, Vassaux, Georges, Harrington, Kevin J
Publicado em 2010

Early achievement and maintenance of stable asthma control using initially higher-dose inhaled...

Por Cheng, Shih-Lung, Wang, Hao-Chien, Kuo, Sow-Hsong
Publicado em 2013

Dasiglucagon Effects on QTc in Healthy Volunteers: A Randomized, Placebo-Controlled, Dose-Escalation, Double-Blind Study

Por Ramin Tehranchi, MD, PhD, MBA, Jonas Pettersson, MD, PhD, Anita E. Melgaard, MSc, Friedeborg Seitz, MD, Anders Valeur, PhD, Stine Just Maarbjerg, PhD
Publicado em 2022-01-01

YM155 reverses cisplatin resistance in head and neck cancer by decreasing cytoplasmic survivin levels

Por Kumar, Bhavna, Yadav, Arti, Lang, James C., Cipolla, Michael, Schmitt, Alessandra C., Arradaza, Nicole, Teknos, Theodoros N., Kumar, Pawan
Publicado em 2012

Novel Insights on the Effect of Nicotine in a Murine Colitis Model

Por AlSharari, Shakir D., Akbarali, Hamid I., Abdullah, Rehab A., Shahab, Omer, Auttachoat, Wimolnut, Ferreira, Gabriela A., White, Kimber L., Lichtman, Aron H., Cabral, Guy A., Damaj, M. Imad
Publicado em 2013

Anticancer activity of streptochlorin, a novel antineoplastic agent, in cholangiocarcinoma

Por Kwak, Tae Won, Shin, Hee Jae, Jeong, Young-Il, Han, Myoung-Eun, Oh, Sae-Ock, Kim, Hyun-Jung, Kim, Do Hyung, Kang, Dae Hwan
Publicado no Drug Des Devel Ther (2015)

Pharmacokinetics, pharmacodynamics, and tolerability of LC350189, a novel xanthine oxidase inhibitor, in healthy subjects

Por Yoon, Seonghae, Shin, Donghoon, Lee, Howard, Jang, In-Jin, Yu, Kyung-Sang
Publicado no Drug Des Devel Ther (2015)

Imepitoin as novel treatment option for canine idiopathic epilepsy: pharmacokinetics, distribution, and metabolism in dogs

Por Rundfeldt, C, Gasparic, A, Wlaź, P
Publicado no J Vet Pharmacol Ther (2014)