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Pharmacokinetics, pharmacodynamics, and tolerability of LC350189, a novel xanthine oxidase inhibitor, in healthy subjects

INTRODUCTION: LC350189 is a novel selective xanthine oxidase inhibitor under clinical development for the management of hyperuricemia in gout patients. The aim of this study was to evaluate the pharmacokinetics, pharmacodynamics, and tolerability of the drug in healthy subjects. METHODS: A dose-bloc...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Yoon, Seonghae, Shin, Donghoon, Lee, Howard, Jang, In-Jin, Yu, Kyung-Sang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560520/
https://ncbi.nlm.nih.gov/pubmed/26357467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86884
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