A Genomic DNA Reporter Screen Identifies Squalene Synthase Inhibitors That Act Cooperatively with Statins to Upregulate the Low-Density Lipoprotein Receptor

Hypercholesterolemia remains one of the leading risk factors for the development of cardiovascular disease. Many large double-blind studies have demonstrated that lowering low-density lipoprotein (LDL) cholesterol using a statin can reduce the risk of having a cardiovascular event by approximately 3...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Kerr, Alastair G., Tam, Lawrence C. S., Hale, Ashley B., Cioroch, Milena, Douglas, Gillian, Agkatsev, Sarina, Hibbitt, Olivia, Mason, Joseph, Holt-Martyn, James, Bataille, Carole J. R., Wynne, Graham M., Channon, Keith M., Russell, Angela J., Wade-Martins, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2017
Assuntos:
Drug Discovery and Translational Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443320/
https://ncbi.nlm.nih.gov/pubmed/28360334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.239574
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados