ロード中...
Long-term Physiologically Regulated Expression of the Low-density Lipoprotein Receptor In Vivo Using Genomic DNA Mini-gene Constructs
Familial hypercholesterolemia (FH) is a condition caused by mutations in the low-density lipoprotein receptor (LDLR) gene. Expression of LDLR is highly regulated and excess receptor expression is cytotoxic. To incorporate essential gene regulation into a gene therapy vector for FH, we generated vect...
保存先:
主要な著者: | , , , , , |
---|---|
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Nature Publishing Group
2009
|
主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2839284/ https://ncbi.nlm.nih.gov/pubmed/19861949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.249 |
タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|