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YM155 reverses cisplatin resistance in head and neck cancer by decreasing cytoplasmic survivin levels

Cisplatin is one of the commonly used chemotherapeutic drugs for the treatment of head and neck squamous cell carcinoma (HNSCC). However, acquisition of cisplatin resistance is common in patients with HNSCC and it often leads to local and distant failure. In this study, we demonstrate that survivin...

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Autors principals: Kumar, Bhavna, Yadav, Arti, Lang, James C., Cipolla, Michael, Schmitt, Alessandra C., Arradaza, Nicole, Teknos, Theodoros N., Kumar, Pawan
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889136/
https://ncbi.nlm.nih.gov/pubmed/22723337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0167
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