YM155 reverses cisplatin resistance in head and neck cancer by decreasing cytoplasmic survivin levels

Cisplatin is one of the commonly used chemotherapeutic drugs for the treatment of head and neck squamous cell carcinoma (HNSCC). However, acquisition of cisplatin resistance is common in patients with HNSCC and it often leads to local and distant failure. In this study, we demonstrate that survivin...

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Hauptverfasser: Kumar, Bhavna, Yadav, Arti, Lang, James C., Cipolla, Michael, Schmitt, Alessandra C., Arradaza, Nicole, Teknos, Theodoros N., Kumar, Pawan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889136/
https://ncbi.nlm.nih.gov/pubmed/22723337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0167
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