The novel Bcl-2 inhibitor ABT-737 is more effective in hypoxia, and is able to reverse hypoxia-induced drug resistance in neuroblastoma cells

Por Klymenko, Tetyana, Brandenburg, Martin, Morrow, Christopher, Dive, Caroline, Makin, Guy
Publicado em 2011

Identification of novel drug targets in bovine respiratory disease: an essential step in applying...

Por Sakharkar, Meena Kishore, Rajamanickam, Karthic, Chandra, Ramesh, Khan, Haseeb A, Alhomida, Abdullah S, Yang, Jian
Publicado no Drug Des Devel Ther (2018)

T-bet expression in rheumatoid arthritis patients with early, disease-modifying anti-rheumatic drug naïve disease is low and correlates with low levels of IL-7 and T-cell dysfunctions

Por Ponchel, F, Brown, AK, Field, SL, Quinn, M, Conaghan, P, Emery, P, Isaacs, JD
Publicado em 2005

Effects of olanzapine on cytokine profile and brain-derived neurotrophic factor in drug-naive subjects with first-episode psychosis

Por Hatziagelaki, Erifili, Tsiavou, Anastasia, Gerasimou, Charilaos, Vavougios, George D., Spathis, Aris, Laskos, Efstathios, Papageorgiou, Charalabos, Douzenis, Athanasios, Christodoulou, Nikos, Stefanis, Nicolaos, Spandidos, Demetrios A., Nikolakakis, Nikolaos, Tsamakis, Konstantinos, Rizos, Emmanouil
Publicado no Exp Ther Med (2019)

Insights into novel emerging epigenetic drugs in myeloid malignancies

Por Chandhok, Namrata S., Prebet, Thomas
Publicado no Ther Adv Hematol (2019)

Prevalence of reverse transcriptase and protease mutations associated with antiretroviral drug resistance among drug-naïve HIV-1 infected pregnant women in Kagera and Kilimanjaro regions, Tanzania

Por Nyombi, Balthazar M, Holm-Hansen, Carol, Kristiansen, Knut I, Bjune, Gunnar, Müller, Fredrik
Publicado em 2008

Brivaracetam: a novel antiepileptic drug for focal-onset seizures

Por Stephen, Linda J., Brodie, Martin J.
Publicado no Ther Adv Neurol Disord (2017)

THER-08. RAPLINK-1 COOPERATES WITH INHIBITORS OF Bcl-2/Bcl-xl TO INDUCE APOPTOSIS IN GLIOBLASTOMA

Por Luo, Xujun, Fan, Qi-Wen, Shokat, Kevan M, Weiss, William A
Publicado no Neuro Oncol (2019)

Pharmacology of Ramelteon, a Selective MT(1)/MT(2) Receptor Agonist: A Novel Therapeutic Drug for Sleep Disorders

Por Miyamoto, Masaomi
Publicado em 2009

Novel swellable polymer of orchidaceae family for gastroretentive drug delivery of famotidine

Por Razavi, Mahboubeh, Nyamathulla, Shaik, Karimian, Hamed, Noordin, Mohamed Ibrahim
Publicado em 2014

Novel C-1 Substituted Cocaine Analogs Unlike Cocaine or Benztropine

Por Reith, Maarten E. A., Ali, Solav, Hashim, Audrey, Sheikh, Imran S., Theddu, Naresh, Gaddiraju, Narendra V., Mehrotra, Suneet, Schmitt, Kyle C., Murray, Thomas F., Sershen, Henry, Unterwald, Ellen M., Davis, Franklin A.
Publicado em 2012

Effect of Metformin Glycinate on Glycated Hemoglobin A1c Concentration and Insulin Sensitivity in Drug-Naive Adult Patients with Type 2 Diabetes Mellitus

Por González-Ortiz, Manuel, Martínez-Abundis, Esperanza, Robles-Cervantes, José A., Ramos-Zavala, Maria G., Barrera-Durán, Carmelita, González-Canudas, Jorge
Publicado em 2012

Novel Screening Assay for the Selective Detection of G-Protein-Coupled Receptor Heteromer Signaling

Por van Rijn, Richard M., Harvey, Jessica H., Brissett, Daniela I., DeFriel, Julia N., Whistler, Jennifer L.
Publicado em 2013

Rigid Adenine Nucleoside Derivatives as Novel Modulators of the Human Sodium Symporters for Dopamine and Norepinephrine

Por Janowsky, Aaron, Tosh, Dilip K., Eshleman, Amy J., Jacobson, Kenneth A.
Publicado no J Pharmacol Exp Ther (2016)

THER-29. NOVEL DUAL EGFR/PI3-KINASE INHIBITORS SHOW ENHANCED POTENCY, STRONGER PATHWAY SUPPRESSION...

Por Sun, Yusha, Bailey, Cavan, Whitehead, Christopher, Sebolt-Leopold, Judith, Chandra, Joya
Publicado no Neuro Oncol (2019)

Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma

Por Li, Mei-Hong, Swenson, Rolf, Harel, Miriam, Jana, Sampa, Stolarzewicz, Erik, Hla, Timothy, Shapiro, Linda H., Ferrer, Fernando
Publicado no J Pharmacol Exp Ther (2015)

Early Human Screening of Medications to Treat Drug Addiction: Novel Paradigms and the Relevance of Pharmacogenetics

Por Perkins, KA, Lerman, C
Publicado em 2011

Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics

Por Liu, Lei, Ma, Ying, Wang, Run-Ling, Xu, Wei-Ren, Wang, Shu-Qing, Chou, Kuo-Chen
Publicado em 2013

Nanolipolee-007, a novel nanoparticle based drug containing leelamine for the treatment of melanoma

Por Gowda, Raghavendra, Madhunapantula, SubbaRao V., Sharma, Arati, Kuzu, Omer F, Robertson, Gavin P.
Publicado no Mol Cancer Ther (2014)

Progranulin: A growth factor, a novel TNFR ligand and a drug target

Por Liu, Chuan-ju, Bosch, Xavier
Publicado no Pharmacol Ther (2011)