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Progranulin: A growth factor, a novel TNFR ligand and a drug target
Progranulin (PGRN) is abundantly expressed in epithelial cells, immune cells, neurons, and chondrocytes, and reportedly contributes to tumorigenesis. PGRN is a crucial mediator of wound healing and tissue repair. PGRN also functions as a neurotrophic factor and mutations in the PGRN gene resulting i...
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| Publicado no: | Pharmacol Ther |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4429904/ https://ncbi.nlm.nih.gov/pubmed/22008260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2011.10.003 |
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