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A Solid-Phase Assay for Studying Direct Binding of Progranulin to TNFR and Progranulin Antagonism of TNF/TNFR Interactions

The discovery that TNF receptors (TNFR) serve as the binding receptors for progranulin (PGRN) reveals the significant role of PGRN in inflammatory and autoimmune diseases, including inflammatory arthritis. Herein we describe a simple, antibody-free analytical assay, i.e., a biotin-based solid-phase...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Tian, Qingyun, Zhao, Shuai, Liu, Chuanju
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406480/
https://ncbi.nlm.nih.gov/pubmed/24788181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-0669-7_14
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