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In vitro physical and functional interaction assays to examine the binding of progranulin derivative Atsttrin to TNFR2 and its anti-TNFα activity
TNFα/TNFR signaling plays a critical role in the pathogenesis of various inflammatory and autoimmune diseases, and anti-TNFα therapies have been accepted as the effective approaches for treating several autoimmune diseases. Progranulin (PGRN), a multi-faced growth-factor like molecule, directly bind...
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| Vydáno v: | Methods Mol Biol |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8112733/ https://ncbi.nlm.nih.gov/pubmed/33185871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-1130-2_8 |
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