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Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models
BACKGROUND: Atsttrin, an engineered protein composed of three tumor necrosis factor receptor (TNFR)-binding fragments of progranulin (PGRN), shows therapeutic effect in multiple murine models of inflammatory arthritis . Additionally, intra-articular delivery of PGRN protects against osteoarthritis (...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Arthritis Res Ther |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5735869/ https://ncbi.nlm.nih.gov/pubmed/29258611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1485-8 |
| Ετικέτες: |
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