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Progranulin: A Promising Therapeutic Target for Rheumatoid Arthritis
Progranulin (PGRN) is an autocrine growth factor with multiple functions. This review provides updates about the interplays of PGRN with extracellular matrix proteins, proteolytic enzymes, inflammatory cytokines, and cell surface receptors in cartilage and arthritis, with a special focus on the inte...
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| Format: | Artigo |
| Jezik: | Inglês |
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2011
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162080/ https://ncbi.nlm.nih.gov/pubmed/21550343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.04.065 |
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