Resultados da pesquisa - (((( j nat comes can now ) OR ( j l compra de neta ))) OR ( ((j lu) OR (j da)) amp camp new ))*

1

Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling

Por Tsai, Su-Yi, Maass, Karen, Lu, Jia, Fishman, Glenn I., Chen, Shuibing, Evans, Todd
Publicado no Stem Cell Reports (2015)

“... for mechanistic studies and drug discovery and also provide new cellular materials for regenerative therapies. A...”
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2

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New insights into the dynamic regulation of water and acid-base balance by renal epithelial cells

Por Brown, Dennis, Bouley, Richard, Pǎunescu, Teodor G., Breton, Sylvie, Lu, Hua A. J.
Publicado em 2012

“... proton-pumping ATPase (V-ATPase) via cAMP to regulate tubular pH. Renal intercalated cells also express...”
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3

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CRTC1-MAML2 fusion-induced lncRNA LINC00473 expression maintains the growth and survival of human mucoepidermoid carcinoma cells

Por Chen, Zirong, Lin, Shuibin, Li, Jian-Liang, Ni, Wei, Guo, Ruifeng, Lu, Jianrong, Kaye, Frederic J., Wu, Lizi
Publicado no Oncogene (2018)

“... cAMP signaling pathway component NONO, enhancing the ability of CRTC1-MAML2 to activate CREB-mediated...”
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4

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Characterization of the Structures of Phosphodiesterase 10 Binding with Adenosine 3´,5´-Monophosphate and Guanosine 3´,5´-Monophosphate by Hybrid Quantum Mechanical/Molecular Mecha...

Por Lu, Haiting, Goren, Alan C., Zhan, Chang-Guo
Publicado em 2010

“... in PDE10-AMP is different from PDE10-GMP. Finally, our results help to understand why PDE10 can hydrolyze...”
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‘Reversine’ and its 2-Substituted Adenine Derivatives as Potent and Selective A(3) Adenosine Receptor Antagonists

Por Perreira, Melissa, Jiang, Jian-kang, Klutz, Athena, Gao, Zhan-Guo, Shainberg, Asher, Lu, Changrui, Thomas, Craig J., Jacobson, Kenneth A.
Publicado em 2005

“...-stimulated cAMP production in stably transfected Chinese hamster ovary (CHO) cells. These results...”
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A Potential Role for Shed Soluble Major Histocompatibility Class I Molecules as Modulators of Neurite Outgrowth

Por Washburn, Lorraine R., Zekzer, Dan, Eitan, Shoshana, Lu, Yuxin, Dang, Hoa, Middleton, Blake, Evans, Christopher J., Tian, Jide, Kaufman, Daniel L.
Publicado em 2011

“... neurons in vitro. The neuroinhibitory effect of sMHCI could be blocked by lowering cAMP levels, suggesting...”
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Disparate roles of retinoid acid signaling molecules in kidney disease

Por Chen, Anqun, Liu, Yu, Lu, Yu, Lee, Kyung, He, John Cijiang
Publicado no Am J Physiol Renal Physiol (2021)

“.... The effects of RA in podocytes are mediated mainly by activation of the cAMP/PKA pathway via RA receptor-α...”
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The Similarities and Diversities of Signal Pathways Leading to Consolidation of Conditioning and Consolidation of Extinction of Fear Memory

Por Lin, Chih-Hung, Yeh, Shiu-Hwa, Lu, Hsin-Yi, Gean, Po-Wu
Publicado no J Neurosci (2003)

“... kinase inhibitor blocked fear training-induced cAMP response element-binding protein (CREB...”
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MicroRNA-506 inhibits esophageal cancer cell proliferation via targeting CREB1

Por Yao, Wen-Jian, Wang, Yong-Lian, Lu, Jian-Guo, Guo, Ling, Qi, Bo, Chen, Zhi-Jun
Publicado no Int J Clin Exp Pathol (2015)

“... the expression and transcription activity of cAMP responsive element binding protein 1 (CREB1). CREB1, tumor...”
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10

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A novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2-adrenergic receptor internalization and down-regulation

Por Jiang, Xiaofeng, Pan, Hui, Nabhan, Joseph F., Krishnan, Ramaswamy, Koziol-White, Cynthia, Panettieri, Reynold A., Lu, Quan
Publicado em 2012

“... reversed agonist-induced endogenous β2AR loss as indicated by an increase in cAMP production. FDPS...”
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11

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A Cell-based PDE4 Assay in 1536-well Plate format for High Throughput Screening

Por Titus, Steven A., Li, Xiao, Southall, Noel, Lu, Jianming, Inglese, James, Brasch, Michael, Austin, Christopher P., Zheng, Wei
Publicado em 2008

“... the hydrolysis of 3', 5'-cyclic nucleotides, such as cyclic adenosine monophosphate (cAMP) and cyclic guanosine...”
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Atherogenic Phospholipids Attenuate Osteogenic Signaling by BMP-2 and Parathyroid Hormone in Osteoblasts

Por Huang, Michael S., Morony, Sean, Lu, Jinxiu, Zhang, Zina, Bezouglaia, Olga, Tseng, Wendy, Tetradis, Sotirios, Demer, Linda L., Tintut, Yin
Publicado em 2007

“... inhibited PTH-induced cAMP production and expression of immediate early genes Nurr1 and IL-6. Results from...”
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EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2–Mediated Renal Water Reabsorption

Por Cheung, Pui W., Nomura, Naohiro, Nair, Anil V., Pathomthongtaweechai, Nutthapoom, Ueberdiek, Lars, Lu, Hua A. Jenny, Brown, Dennis, Bouley, Richard
Publicado no J Am Soc Nephrol (2016)

“... signaling. Because potential therapies for NDI that target the canonical VP/cAMP/protein kinase A pathway...”
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Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy.

Por Zhao, Yang, Chang, Ziyi, Zhao, Guizhen, Lu, Haocheng, Xiong, Wenhao, Liang, Wenying, Wang, Huilun, Villacorta, Luis, Garcia-Barrio, Minerva T., Zhu, Tianqing, Guo, Yanhong, Fan, Yanbo, Chang, Lin, Schopfer, Francisco J., Freeman, Bruce A., Zhang, Jifeng, Chen, Y. Eugene
Publicado no Cardiovasc Drugs Ther (2020)

“... on the inhibition of macrophage prostaglandin E2 (PGE(2))-induced PGE(2) receptor 4 (EP4) cAMP signaling, known...”
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Structural determinants in the second intracellular loop of the human cannabinoid CB(1) receptor mediate selective coupling to G(s) and G(i)

Por Chen, XP, Yang, W, Fan, Y, Luo, JS, Hong, K, Wang, Z, Yan, JF, Chen, X, Lu, JX, Benovic, JL, Zhou, NM
Publicado em 2010

“... coupled to the G(i) form of G proteins, through which it negatively regulates cAMP accumulation. Here, we...”
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From structure to the dynamic regulation of a molecular switch: A journey over 3 decades

Por Taylor, Susan S., Wu, Jian, Bruystens, Jessica G.H., Del Rio, Jason C., Lu, Tsan-Wen, Kornev, Alexandr P., Ten Eyck, Lynn F.
Publicado no J Biol Chem (2021)

“... with the protein kinases using cAMP-dependent protein kinase as a prototype. We summarize what we have learned...”
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Vascular Endothelial Growth Factor (VEGF) Receptor-2 Tyrosine 1175 Signaling Controls VEGF-induced von Willebrand Factor Release from Endothelial Cells via Phospholipase C-γ1- and...

Por Xiong, Yan, Huo, Yingqing, Chen, Chao, Zeng, Huiyan, Lu, Xiaofan, Wei, Chaoliang, Ruan, Changgeng, Zhang, Xiaoyu, Hu, Zhenqian, Shibuya, Masabumi, Luo, Jincai
Publicado em 2009

“... pathway. We found that cAMP/protein kinase A (PKA) signaling is required for full vWF release. Importantly...”
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Dopamine Induces a PI3-Kinase-Independent Activation of Akt in Striatal Neurons: A New Route to cAMP Response Element-Binding Protein Phosphorylation

Por Brami-Cherrier, Karen, Valjent, Emmanuel, Garcia, Marta, Pagès, Christiane, Hipskind, Robert A., Caboche, Jocelyne
Publicado no J Neurosci (2002)

“..., overexpression of a mutant form of Akt that cannot be activated impaired cAMP response element-binding protein...”
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Temporal Effects of Vascular Endothelial Growth Factor and cAMP on the Blood-Brain Barrier Solute permeability in vivo

Por Shi, Lingyan, Zeng, Min, Fu, Bingmei M.
Publicado no J Neurosci Res (2014)

“... monophosphate (cAMP) levels can inhibit the VEGF-induced acute hyperpermeability, we employed multiphoton...”
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Molecular cloning and subcellular distribution of the novel PDE4B4 cAMP-specific phosphodiesterase isoform.

Por Shepherd, Malcolm, McSorley, Theresa, Olsen, Aileen E, Johnston, Lee Ann, Thomson, Neil C, Baillie, George S, Houslay, Miles D, Bolger, Graeme B
Publicado em 2003

“...We have isolated cDNAs encoding PDE4B4, a new cAMP-specific phosphodiesterase (PDE4) isoform...”
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