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Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling
Dysfunction of the specialized cardiac conduction system (CCS) is associated with life-threatening arrhythmias. Strategies to derive CCS cells, including rare Purkinje cells (PCs), would facilitate models for mechanistic studies and drug discovery and also provide new cellular materials for regenera...
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Publicado no: | Stem Cell Reports |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4471825/ https://ncbi.nlm.nih.gov/pubmed/26028533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.04.015 |
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