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Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling

Dysfunction of the specialized cardiac conduction system (CCS) is associated with life-threatening arrhythmias. Strategies to derive CCS cells, including rare Purkinje cells (PCs), would facilitate models for mechanistic studies and drug discovery and also provide new cellular materials for regenera...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Tsai, Su-Yi, Maass, Karen, Lu, Jia, Fishman, Glenn I., Chen, Shuibing, Evans, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471825/
https://ncbi.nlm.nih.gov/pubmed/26028533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.04.015
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