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‘Reversine’ and its 2-Substituted Adenine Derivatives as Potent and Selective A(3) Adenosine Receptor Antagonists
The dedifferentiation agent ‘reversine’ (2-(4-morpholinoanilino)-N(6)-cyclohexyladenine 2) was found to be a moderately potent antagonist for the human A(3) adenosine receptor (AR) with a K(i) value 0.66 μM. This result prompted an exploration of the structure-activity relationship of related deriva...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474371/ https://ncbi.nlm.nih.gov/pubmed/16033270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm050221l |
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