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Medicinal Chemistry of the A(3) Adenosine Receptor: Agonists, Antagonists, and Receptor Engineering

A(3) adenosine receptor (A(3)AR) ligands have been modified to optimize their interaction with the A(3)AR. Most of these modifications have been made to the N(6) and C2 positions of adenine as well as the ribose moiety, and using a combination of these substitutions leads to the most efficacious, se...

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Détails bibliographiques
Auteurs principaux: Jacobson, Kenneth A., Klutz, Athena M., Tosh, Dilip K., Ivanov, Andrei A., Preti, Delia, Baraldi, Pier Giovanni
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413728/
https://ncbi.nlm.nih.gov/pubmed/19639281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-540-89615-9_5
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