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Medicinal Chemistry of the A(3) Adenosine Receptor: Agonists, Antagonists, and Receptor Engineering

A(3) adenosine receptor (A(3)AR) ligands have been modified to optimize their interaction with the A(3)AR. Most of these modifications have been made to the N(6) and C2 positions of adenine as well as the ribose moiety, and using a combination of these substitutions leads to the most efficacious, se...

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Detalhes bibliográficos
Main Authors: Jacobson, Kenneth A., Klutz, Athena M., Tosh, Dilip K., Ivanov, Andrei A., Preti, Delia, Baraldi, Pier Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413728/
https://ncbi.nlm.nih.gov/pubmed/19639281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-540-89615-9_5
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