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Medicinal Chemistry of the A(3) Adenosine Receptor: Agonists, Antagonists, and Receptor Engineering

A(3) adenosine receptor (A(3)AR) ligands have been modified to optimize their interaction with the A(3)AR. Most of these modifications have been made to the N(6) and C2 positions of adenine as well as the ribose moiety, and using a combination of these substitutions leads to the most efficacious, se...

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Hlavní autoři: Jacobson, Kenneth A., Klutz, Athena M., Tosh, Dilip K., Ivanov, Andrei A., Preti, Delia, Baraldi, Pier Giovanni
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413728/
https://ncbi.nlm.nih.gov/pubmed/19639281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-540-89615-9_5
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