Aptamer-Mediated Codelivery of Doxorubicin and NF-κB Decoy Enhances Chemosensitivity of Pancreatic Tumor Cells

Por Porciani, David, Tedeschi, Lorena, Marchetti, Laura, Citti, Lorenzo, Piazza, Vincenzo, Beltram, Fabio, Signore, Giovanni
Publicado no Mol Ther Nucleic Acids (2015)

Conditionally replicating adenovirus prevents pluripotent stem cell–derived teratoma by specifically eliminating undifferentiated cells

Por Mitsui, Kaoru, Ide, Kanako, Takayama, Akiko, Wada, Tadahisa, Irie, Rie, Kosai, Ken-ichiro
Publicado no Mol Ther Methods Clin Dev (2015)

Neuroprotective effect of β-asarone against Alzheimer’s disease: regulation of synaptic plasticity by increased expression of SYP and GluR1

Por Liu, Si-jun, Yang, Cong, Zhang, Yue, Su, Ru-yu, Chen, Jun-li, Jiao, Meng-meng, Chen, Hui-fang, Zheng, Na, Luo, Si, Chen, Yun-bo, Quan, Shi-jian, Wang, Qi
Publicado no Drug Des Devel Ther (2016)

Pharmacogenomic Discovery to Function and Mechanism: Breast Cancer as a Case Study

Por Wang, Liewei, Ingle, James, Weinshilboum, Richard
Publicado no Clin Pharmacol Ther (2017)

Synthesis, antimicrobial, and antiproliferative activities of substituted phenylfuranylnicotinamidines

Por Youssef, Magdy M, Arafa, Reem K, Ismail, Mohamed A
Publicado no Drug Des Devel Ther (2016)

Apomine Enhances the Antitumor Effects of Lovastatin on Myeloma Cells by Down-Regulating 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase

Por Roelofs, Anke J., Edwards, Claire M., Russell, R. Graham G., Ebetino, F. Hal, Rogers, Michael J., Hulley, Philippa A.
Publicado em 2007

Therapeutic Targeting of Protein Kinase CK2 Gene Expression in Feline Oral Squamous Cell Carcinoma: A Naturally Occurring Large-Animal Model of Head and Neck Cancer(†)

Por Cannon, Claire M., Trembley, Janeen H., Kren, Betsy T., Unger, Gretchen M., O'Sullivan, M. Gerard, Cornax, Ingrid, Modiano, Jaime F., Ahmed, Khalil
Publicado no Hum Gene Ther Clin Dev (2017)

Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer’s disease

Por Blain, Jean-François, Bursavich, Matthew G., Freeman, Emily A., Hrdlicka, Lori A., Hodgdon, Hilliary E., Chen, Ting, Costa, Don E., Harrison, Bryce A., Kapadnis, Sudarshan, Murphy, Deirdre A., Nolan, Scott, Tu, Zhiming, Tang, Cuyue, Burnett, Duane A., Patzke, Holger, Koenig, Gerhard
Publicado no Alzheimers Res Ther (2016)

Dasiglucagon Effects on QTc in Healthy Volunteers: A Randomized, Placebo-Controlled, Dose-Escalation, Double-Blind Study

Por Ramin Tehranchi, MD, PhD, MBA, Jonas Pettersson, MD, PhD, Anita E. Melgaard, MSc, Friedeborg Seitz, MD, Anders Valeur, PhD, Stine Just Maarbjerg, PhD
Publicado em 2022-01-01

The combination of blueberry juice and probiotics reduces apoptosis of alcoholic fatty liver of mice by affecting SIRT1 pathway

Por Zhu, Juanjuan, Ren, Tingting, Zhou, Mingyu, Cheng, Mingliang
Publicado no Drug Des Devel Ther (2016)

ATP Citrate Lyase Mediates Resistance of Colorectal Cancer Cells to SN38

Por Zhou, Yunfei, Bollu, Lakshmi Reddy, Tozzi, Federico, Ye, Xiangcang, Bhattacharya, Rajat, Gao, Guang, Dupre, Elizabeth, Xia, Ling, Lu, Jia, Fan, Fan, Bellister, Seth, Ellis, Lee M, Weihua, Zhang
Publicado no Mol Cancer Ther (2013)

Inhibitors of the anti-apoptotic Bcl-2 proteins: a patent review

Por Bajwa, Naval, Liao, Chenzhong, Nikolovska-Coleska, Zaneta
Publicado em 2011

Safinamide in the management of patients with Parkinson’s disease not stabilized on levodopa: a review of the current clinical evidence

Por Bette, Sagari, Shpiner, Danielle S, Singer, Carlos, Moore, Henry
Publicado no Ther Clin Risk Manag (2018)

Update on long-term efficacy and safety of dapagliflozin in patients with type 2 diabetes mellitus

Por Liakos, Aris, Karagiannis, Thomas, Bekiari, Eleni, Boura, Panagiota, Tsapas, Apostolos
Publicado no Ther Adv Endocrinol Metab (2015)

Targeting lipid metabolism for the treatment of Anaplastic Thyroid Carcinoma

Por von Roemeling, Christina A., Copland, John A.
Publicado no Expert Opin Ther Targets (2015)

Application of Direct Renin Inhibition to Chronic Kidney Disease

Por Mende, Christian W.
Publicado em 2010

The Emerging Role of Lenalidomide in the Management of Lymphoid Malignancies

Por Hernandez-Ilizaliturri, Francisco J., Batoo, Sameer A.
Publicado em 2011

Salvage therapies in relapsed and/or refractory myeloma: what is current and what is the future?

Por Thumallapally, Nishitha, Yu, Hana, Asti, Divya, Vennepureddy, Adarsh, Terjanian, Terenig
Publicado no Onco Targets Ther (2016)

Constitutively active form of natriuretic peptide receptor 2 ameliorates experimental pulmonary arterial hypertension

Por Nawa, Nobutoshi, Ishida, Hidekazu, Katsuragi, Shinichi, Baden, Hiroki, Takahashi, Kunihiko, Higeno, Ryota, Torigoe, Fumiko, Mihara, Seiko, Narita, Jun, Miura, Kohji, Nakamura, Kazufumi, Kogaki, Shigetoyo, Ozono, Keiichi
Publicado no Mol Ther Methods Clin Dev (2016)

The antiviral compound BIT225 inhibits HIV-1 replication in myeloid dendritic cells

Por Khoury, Gabriela, Ewart, Gary, Luscombe, Carolyn, Miller, Michelle, Wilkinson, John
Publicado no AIDS Res Ther (2016)