Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer’s disease

Por Blain, Jean-François, Bursavich, Matthew G., Freeman, Emily A., Hrdlicka, Lori A., Hodgdon, Hilliary E., Chen, Ting, Costa, Don E., Harrison, Bryce A., Kapadnis, Sudarshan, Murphy, Deirdre A., Nolan, Scott, Tu, Zhiming, Tang, Cuyue, Burnett, Duane A., Patzke, Holger, Koenig, Gerhard
Publicado no Alzheimers Res Ther (2016)

Discovery and Development of LX7101, a Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma

Por Harrison, Bryce A., Almstead, Zheng Y., Burgoon, Hugh, Gardyan, Michael, Goodwin, Nicole C., Healy, Jason, Liu, Ying, Mabon, Ross, Marinelli, Brett, Samala, Lakshman, Zhang, Yulian, Stouch, Terry R., Whitlock, N. Andrew, Gopinathan, Suma, McKnight, Beth, Wang, Shuli, Patel, Nita, Wilson, Alan G. E., Hamman, Brian D., Rice, Dennis S., Rawlins, David B.
Publicado no ACS Med Chem Lett (2014)