Ischemic Preconditioning, Retinal Neuroprotection and Histone Deacetylase Activities

Por Fan, Jie, Alsarraf, Oday, Chou, C. James, Yates, Phillip W., Goodwin, Nicole C., Rice, Dennis S., Crosson, Craig E.
Publicado no Exp Eye Res (2016)

Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation

Por Goodwin, Nicole C., Cianchetta, Giovanni, Burgoon, Hugh A., Healy, Jason, Mabon, Ross, Strobel, Eric D., Allen, Jason, Wang, Shuli, Hamman, Brian D., Rawlins, David B.
Publicado no ACS Med Chem Lett (2014)

LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2

Por Powell, David R, Smith, Melinda G, Doree, Deon D, Harris, Angela L, Xiong, Wendy W, Mseeh, Faika, Wilson, Alan, Gopinathan, Suma, Diaz, Damaris, Goodwin, Nicole C, Harrison, Bryce, Strobel, Eric, Rawlins, David B, Carson, Ken, Zambrowicz, Brian, Ding, Zhi-Ming
Publicado no Pharmacol Res Perspect (2015)

Discovery and Development of LX7101, a Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma

Por Harrison, Bryce A., Almstead, Zheng Y., Burgoon, Hugh, Gardyan, Michael, Goodwin, Nicole C., Healy, Jason, Liu, Ying, Mabon, Ross, Marinelli, Brett, Samala, Lakshman, Zhang, Yulian, Stouch, Terry R., Whitlock, N. Andrew, Gopinathan, Suma, McKnight, Beth, Wang, Shuli, Patel, Nita, Wilson, Alan G. E., Hamman, Brian D., Rice, Dennis S., Rawlins, David B.
Publicado no ACS Med Chem Lett (2014)