Protein kinase CK2 impact on intracellular calcium homeostasis in prostate cancer

door Afzal, Muhammad, Kren, Betsy T., Naveed, A. Khaliq, Trembley, Janeen H., Ahmed, Khalil
Gepubliceerd in Mol Cell Biochem (2020)

Protein kinase CK2 inhibition induces cell death via early impact on mitochondrial function*

door Qaiser, Fatima, Trembley, Janeen H., Kren, Betsy T., Wu, Jing-Jiang, Naveed, A. Khaliq, Ahmed, Khalil
Gepubliceerd in 2014

Growth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia hydaspica: Involvement of multiple signal transduction pathways

door Afsar, Tayyaba, Trembley, Janeen H., Salomon, Christine E., Razak, Suhail, Khan, Muhammad Rashid, Ahmed, Khalil
Gepubliceerd in Sci Rep (2016)

Emergence of Protein Kinase CK2 as a Key Target in Cancer Therapy

door Trembley, Janeen H., Chen, Zhong, Unger, Gretchen, Slaton, Joel, Kren, Betsy T., Van Waes, Carter, Ahmed, Khalil
Gepubliceerd in 2010

Improving Health Care for Veterans With Gulf War Illness

door Baldwin, Nicole, Rudquist, Rebecca R., Lava-Parmele, Susan, Trembley, Janeen H., Butterick, Tammy A., Bach, Ronald R.
Gepubliceerd in Fed Pract (2019)

CK2 Pro-Survival Role in Prostate Cancer Is Mediated via Maintenance and Promotion of Androgen Receptor and NFκB p65 Expression

door Trembley, Janeen H., Kren, Betsy T., Abedin, Md. J., Shaughnessy, Daniel P., Li, Yingming, Dehm, Scott M., Ahmed, Khalil
Gepubliceerd in Pharmaceuticals (Basel) (2019)

CX-4945 and siRNA-Mediated Knockdown of CK2 Improves Cisplatin Response in HPV(+) and HPV(−) HNSCC Cell Lines

door Trembley, Janeen H., Li, Bin, Kren, Betsy T., Gravely, Amy A., Caicedo-Granados, Emiro, Klein, Mark A., Ahmed, Khalil
Gepubliceerd in Biomedicines (2021)

Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy

door Kren, Betsy T, Unger, Gretchen M, Abedin, Md J, Vogel, Rachel I, Henzler, Christine M, Ahmed, Khalil, Trembley, Janeen H
Gepubliceerd in Breast Cancer Res (2015)

CK2 Molecular Targeting—Tumor Cell-Specific Delivery of RNAi in Various Models of Cancer

door Trembley, Janeen H., Kren, Betsy T., Abedin, Md. Joynal, Vogel, Rachel I., Cannon, Claire M., Unger, Gretchen M., Ahmed, Khalil
Gepubliceerd in Pharmaceuticals (Basel) (2017)

CDK11 Loss Induces Cell Cycle Dysfunction and Death of BRAF and NRAS Melanoma Cells

door Ahmed, Rehana L., Shaughnessy, Daniel P., Knutson, Todd P., Vogel, Rachel I., Ahmed, Khalil, Kren, Betsy T., Trembley, Janeen H.
Gepubliceerd in Pharmaceuticals (Basel) (2019)

Gulf War Illness-associated increases in blood levels of interleukin 6 and C-reactive protein: biomarker evidence of inflammation

door Butterick, Tammy A., Trembley, Janeen H., Hocum Stone, Laura L., Muller, Clemma J., Rudquist, Rebecca R., Bach, Ronald R.
Gepubliceerd in BMC Res Notes (2019)

Activation of Pre-mRNA Splicing by Human RNPS1 Is Regulated by CK2 Phosphorylation

door Trembley, Janeen H., Tatsumi, Sawako, Sakashita, Eiji, Loyer, Pascal, Slaughter, Clive A., Suzuki, Hitoshi, Endo, Hitoshi, Kidd, Vincent J., Mayeda, Akila
Gepubliceerd in 2005

Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells

door Trembley, Janeen H., Unger, Gretchen M., Korman, Vicci L., Tobolt, Diane K., Kazimierczuk, Zygmunt, Pinna, Lorenzo A., Kren, Betsy T., Ahmed, Khalil
Gepubliceerd in 2011

Mechanism and efficacy of sub-50 nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma

door Unger, Gretchen M., Kren, Betsy T., Korman, Vicci L., Kimbrough, Tyler G., Vogel, Rachel I., Ondrey, Frank G., Trembley, Janeen H., Ahmed, Khalil
Gepubliceerd in 2014

Therapeutic Targeting of Protein Kinase CK2 Gene Expression in Feline Oral Squamous Cell Carcinoma: A Naturally Occurring Large-Animal Model of Head and Neck Cancer(†)

door Cannon, Claire M., Trembley, Janeen H., Kren, Betsy T., Unger, Gretchen M., O'Sullivan, M. Gerard, Cornax, Ingrid, Modiano, Jaime F., Ahmed, Khalil
Gepubliceerd in Hum Gene Ther Clin Dev (2017)

Evaluation of protein kinase CK2 as a therapeutic target for squamous cell carcinoma of cats

door Cannon, Claire M., Trembley, Janeen H., Kren, Betsy T., Unger, Gretchen M., O’Sullivan, M. Gerard, Cornax, Ingrid, Modiano, Jaime F., Ahmed, Khalil
Gepubliceerd in Am J Vet Res (2017)

The RNA Binding Motif Protein 15B (RBM15B/OTT3) Is a Functional Competitor of Serine-Arginine (SR) Proteins and Antagonizes the Positive Effect of the CDK11(p110)-Cyclin L2α Comple...

door Loyer, Pascal, Busson, Adeline, Trembley, Janeen H., Hyle, Judith, Grenet, Jose, Zhao, Wei, Ribault, Catherine, Montier, Tristan, Kidd, Vincent J., Lahti, Jill M.
Gepubliceerd in 2011

Tenfibgen-DMAT Nanocapsule Delivers CK2 Inhibitor DMAT to Prostate Cancer Xenograft Tumors Causing Inhibition of Cell Proliferation

door Trembley, Janeen H., Unger, Gretchen M., Gomez, Omar Cespedes, Abedin, J., Korman, Vicci L., Vogel, Rachel I., Niehans, Gloria, Kren, Betsy T., Ahmed, Khalil
Gepubliceerd in Mol Cell Pharmacol (2014)

Examination of CK2α and NF-κB p65 expression in human benign prostatic hyperplasia and prostate cancer tissues

door Qaiser, Fatima, Trembley, Janeen H., Sadiq, Sarah, Muhammad, Iqbal, Younis, Rubina, Hashmi, Shoaib Naiyar, Murtaza, Badar, Rector, Thomas S., Naveed, Abdul Khaliq, Ahmed, Khalil
Gepubliceerd in Mol Cell Biochem (2016)

Systemic administration of antisense oligonucleotides simultaneously targeting CK2α and α′ subunits reduces orthotopic xenograft prostate tumors in mice

door Trembley, Janeen H., Unger, Gretchen M., Tobolt, Diane K., Korman, Vicci L., Wang, Guixia, Ahmad, Kashif A., Slaton, Joel W., Kren, Betsy T., Ahmed, Khalil
Gepubliceerd in 2011