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CK2 Pro-Survival Role in Prostate Cancer Is Mediated via Maintenance and Promotion of Androgen Receptor and NFκB p65 Expression

The prosurvival protein kinase CK2, androgen receptor (AR), and nuclear factor kappa B (NFκB) interact in the function of prostate cells, and there is evidence of crosstalk between these signals in the pathobiology of prostate cancer (PCa). As CK2 is elevated in PCa, and AR and NFκB are involved in...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Trembley, Janeen H., Kren, Betsy T., Abedin, Md. J., Shaughnessy, Daniel P., Li, Yingming, Dehm, Scott M., Ahmed, Khalil
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6631211/
https://ncbi.nlm.nih.gov/pubmed/31197122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12020089
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