The RNA Binding Motif Protein 15B (RBM15B/OTT3) Is a Functional Competitor of Serine-Arginine (SR) Proteins and Antagonizes the Positive Effect of the CDK11(p110)-Cyclin L2α Complex on Splicing

Here, we report the identification of the RNA binding motif protein RBM15B/OTT3 as a new CDK11(p110) binding partner that alters the effects of CDK11 on splicing. RBM15B was initially identified as a binding partner of the Epstein-Barr virus mRNA export factor and, more recently, as a cofactor of th...

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Detalhes bibliográficos
Main Authors: Loyer, Pascal, Busson, Adeline, Trembley, Janeen H., Hyle, Judith, Grenet, Jose, Zhao, Wei, Ribault, Catherine, Montier, Tristan, Kidd, Vincent J., Lahti, Jill M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012969/
https://ncbi.nlm.nih.gov/pubmed/21044963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.192518
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