Mechanism and efficacy of sub-50 nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma

Improved survival for HNC patients with recurrent and metastatic disease warrants that cancer therapy is specific with protected delivery of the therapeutic agent to primary and metastatic cancer cells. A further objective should be that downregulation of the intracellular therapy target leads to ce...

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Detalhes bibliográficos
Main Authors: Unger, Gretchen M., Kren, Betsy T., Korman, Vicci L., Kimbrough, Tyler G., Vogel, Rachel I., Ondrey, Frank G., Trembley, Janeen H., Ahmed, Khalil
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126856/
https://ncbi.nlm.nih.gov/pubmed/24867250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0166
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