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Mechanism and efficacy of sub-50 nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma

Improved survival for HNC patients with recurrent and metastatic disease warrants that cancer therapy is specific with protected delivery of the therapeutic agent to primary and metastatic cancer cells. A further objective should be that downregulation of the intracellular therapy target leads to ce...

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Bibliografiske detaljer
Main Authors: Unger, Gretchen M., Kren, Betsy T., Korman, Vicci L., Kimbrough, Tyler G., Vogel, Rachel I., Ondrey, Frank G., Trembley, Janeen H., Ahmed, Khalil
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126856/
https://ncbi.nlm.nih.gov/pubmed/24867250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0166
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