Tenfibgen Ligand Nanoencapsulation Delivers Bi-Functional Anti-CK2 RNAi Oligomer to Key Sites for Prostate Cancer Targeting Using Human Xenograft Tumors in Mice

Protected and specific delivery of nucleic acids to malignant cells remains a highly desirable approach for cancer therapy. Here we present data on the physical and chemical characteristics, mechanism of action, and pilot therapeutic efficacy of a tenfibgen (TBG)-shell nanocapsule technology for tum...

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Detalhes bibliográficos
Main Authors: Trembley, Janeen H., Unger, Gretchen M., Korman, Vicci L., Abedin, Md. Joynal, Nacusi, Lucas P., Vogel, Rachel I., Slaton, Joel W., Kren, Betsy T., Ahmed, Khalil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198192/
https://ncbi.nlm.nih.gov/pubmed/25333839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109970
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