CK2 modulation of NF-kappaB, TP53 and the malignant phenotype in head and neck cancer by anti-CK2 oligonucleotides in vitro or in vivo via sub-50 nm nanocapsules

PURPOSE: To investigate the expression of CK2 subunits, and CK2 effects on NF-κB and TP53 mediated signal activation and gene expression, the malignant phenotype, and chemosensitivity in head and neck squamous cell carcinoma (HNSCC) in vitro and in vivo. EXPERIMENTAL DESIGN: Protein expression of CK...

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Main Authors: Brown, Matthew S., Diallo, Oumou T., Hu, Michael, Ehsanian, Reza, Yang, Xinping, Arun, Pattatheyil, Lu, Hai, Korman, Vicci, Unger, Gretchen, Ahmed, Khalil, Van Waes, Carter, Chen, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861417/
https://ncbi.nlm.nih.gov/pubmed/20371694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-3200
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