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I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.
I kappaB alpha is an inhibitor protein that prevents nuclear transport-and activation of the transcription factor NF-kappaB. In acute inflammation, NF-kappaB is activated and increases the expression of several pro-inflammatory cytokine and chemokine genes. Glucocorticoids counteract this process. I...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170096/ https://ncbi.nlm.nih.gov/pubmed/9303314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.15.4698 |
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