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Inhibitors of the anti-apoptotic Bcl-2 proteins: a patent review

INTRODUCTION: The B-cell lymphoma-2 (Bcl-2) family of proteins is central to the regulation of apoptosis, which is vital for proper tissue development and cellular homeostasis. Anti-apoptotic proteins, members of the Bcl-2 family, are an important survival factor for many cancers and their overexpre...

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Detalhes bibliográficos
Main Authors: Bajwa, Naval, Liao, Chenzhong, Nikolovska-Coleska, Zaneta
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547649/
https://ncbi.nlm.nih.gov/pubmed/22195752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543776.2012.644274
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