41
“... recombinase-activating genes RAG1 and RAG2, whose aberrant activity has been implicated in chromosomal...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
42
Por Chen, Karin, Wu, Wilfred, Mathew, Divij, Zhang, Yuhua, Browne, Sarah K., Rosen, Lindsey B., McManus, Meghann P., Pulsipher, Michael A., Yandell, Mark, Bohnsack, John F., Jorde, Lynn B., Notarangelo, Luigi D., Walter, Jolan E.
Publicado em 2014
Obter o texto integralPublicado em 2014
Obter o texto integral
Obter o texto integral
Artigo
43
“...Summary: In vertebrate V(D)J recombination, it remains unclear how the RAG complex coordinates its...”
Obter o texto integral
Obter o texto integral
Artigo
44
45
46
“...During B and T cell development, the lymphoid-specific proteins RAG1 and RAG2 act together...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
47
“...The RAG complex in vertebrate V(D)J recombination must coordinate its catalytic steps with its...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
48
“...Hypomorphic Rag mutations in humans cause Omenn Syndrome (OS) a severe immunodeficiency associated...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
49
“...The lymphoid-specific proteins RAG1 and RAG2 initiate V(D)J recombination by introducing DNA double...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
50
“...In addition to their essential role in V(D)J recombination, the RAG proteins function as a...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
51
“...The RAG1 and RAG2 proteins catalyze the site-specific DNA cleavage reactions in V(D)J recombination...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
52
“...ABSTRACT: The RAG1 and RAG2 proteins are essential subunits of the V(D)J recombinase...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
53
Por Zhang, Yu-Hang, Shetty, Keerthi, Surleac, Marius D., Petrescu, Andrei J., Schatz, David G.
Publicado no J Biol Chem (2015)
“...The RAG endonuclease consists of RAG1, which contains the active site for DNA cleavage, and RAG2...”Publicado no J Biol Chem (2015)
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
54
“...V(D)J recombination is initiated by the binding of the RAG1 and RAG2 proteins to recombination...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
55
“...RAG1 and RAG2 initiate V(D)J recombination, the process of rearranging the antigen-binding domain...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
56
“...As a probe of whether RAG-1 and RAG-2 gene products activate other genes or form part...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
57
“...During V(D)J recombination two proteins, RAG1 and RAG2, assemble as a protein-DNA complex...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
58
“...The RAG1 and RAG2 proteins initiate V(D)J recombination by introducing double-strand breaks...”
Obter o texto integral
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo
59
Publicado em 1996
“... and T lymphocytes is dependent on the expression of two recombinant activation genes, Rag-1 and Rag-2. Here, we show...”Obter o texto integral
Obter o texto integral
Artigo
60
Por Lescale, Chloé, Abramowski, Vincent, Bedora-Faure, Marie, Murigneux, Valentine, Vera, Gabriella, Roth, David B., Revy, Patrick, de Villartay, Jean-Pierre, Deriano, Ludovic
Publicado no Nat Commun (2016)
“...-standing hypothesis proposes that, in addition to its canonical nuclease activity, the RAG1/2 proteins...”Publicado no Nat Commun (2016)
Obter o texto integral
Obter o texto integral
Obter o texto integral
Artigo