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A non-sequence specific DNA binding mode of RAG1 is inhibited by RAG2
The RAG1 and RAG2 proteins catalyze the site-specific DNA cleavage reactions in V(D)J recombination, the process that assembles antigen receptor genes from component gene segments during lymphocyte development. The first step towards the DNA cleavage reaction is the sequence-specific association of...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659343/ https://ncbi.nlm.nih.gov/pubmed/19232525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.02.020 |
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