लोड हो रहा है...
DNA Cleavage Activity of the V(D)J Recombination Protein RAG1 Is Autoregulated
RAG1 and RAG2 catalyze the first DNA cleavage steps in V(D)J recombination. We demonstrate that the isolated central domain of RAG1 has inherent single-stranded (ss) DNA cleavage activity, which does not require, but is enhanced by, RAG2. The central domain, therefore, contains the active-site resid...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Microbiology
2004
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC444861/ https://ncbi.nlm.nih.gov/pubmed/15254250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.15.6850-6860.2004 |
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