Detection of RAG Protein-V(D)J Recombination Signal Interactions Near the Site of DNA Cleavage by UV Cross-Linking

V(D)J recombination is initiated by double-strand cleavage at recombination signal sequences (RSSs). DNA cleavage is mediated by the RAG1 and RAG2 proteins. Recent experiments describing RAG protein-RSS complexes, while defining the interaction of RAG1 with the nonamer, have not assigned contacts im...

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Bibliographic Details
Main Authors: Eastman, Quinn M., Villey, Isabelle J., Schatz, David G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC84213/
https://ncbi.nlm.nih.gov/pubmed/10207102
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