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DNA mismatches and GC-rich motifs target transposition by the RAG1/RAG2 transposase

In addition to their essential role in V(D)J recombination, the RAG proteins function as a transposase capable of inserting the V(D)J recombination intermediate, the signal end DNA fragment, into target DNA. RAG-mediated transposition has been suggested to contribute to genome instability and the de...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Tsai, Chia-Lun, Chatterji, Monalisa, Schatz, David G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275461/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576304/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg819
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