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DNA mismatches and GC-rich motifs target transposition by the RAG1/RAG2 transposase
In addition to their essential role in V(D)J recombination, the RAG proteins function as a transposase capable of inserting the V(D)J recombination intermediate, the signal end DNA fragment, into target DNA. RAG-mediated transposition has been suggested to contribute to genome instability and the de...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC275461/ https://ncbi.nlm.nih.gov/pubmed/14576304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg819 |
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