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DNA mismatches and GC-rich motifs target transposition by the RAG1/RAG2 transposase

In addition to their essential role in V(D)J recombination, the RAG proteins function as a transposase capable of inserting the V(D)J recombination intermediate, the signal end DNA fragment, into target DNA. RAG-mediated transposition has been suggested to contribute to genome instability and the de...

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Bibliografske podrobnosti
Main Authors: Tsai, Chia-Lun, Chatterji, Monalisa, Schatz, David G.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC275461/
https://ncbi.nlm.nih.gov/pubmed/14576304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg819
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