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Inverse transposition by the RAG1 and RAG2 proteins: role reversal of donor and target DNA
The lymphoid-specific proteins RAG1 and RAG2 initiate V(D)J recombination by introducing DNA double-strand breaks at the recombination signal sequences (RSSs). In addition to DNA cleavage, the versatile RAG1/2 complex is capable of catalyzing several other reactions, including hybrid joint formation...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136934/ https://ncbi.nlm.nih.gov/pubmed/12456668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf630 |
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