RAG Transposase Can Capture and Commit to Target DNA before or after Donor Cleavage
The discovery that the V(D)J recombinase functions as a transposase in vitro suggests that transposition by this system might be a potent source of genomic instability. To gain insight into the mechanisms that regulate transposition, we investigated a phenomenon termed target commitment that reflect...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2001
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.13.4302-4310.2001 |
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