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RAG Transposase Can Capture and Commit to Target DNA before or after Donor Cleavage
The discovery that the V(D)J recombinase functions as a transposase in vitro suggests that transposition by this system might be a potent source of genomic instability. To gain insight into the mechanisms that regulate transposition, we investigated a phenomenon termed target commitment that reflect...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology
2001
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87090/ https://ncbi.nlm.nih.gov/pubmed/11390658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.13.4302-4310.2001 |
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