RAG Transposase Can Capture and Commit to Target DNA before or after Donor Cleavage
The discovery that the V(D)J recombinase functions as a transposase in vitro suggests that transposition by this system might be a potent source of genomic instability. To gain insight into the mechanisms that regulate transposition, we investigated a phenomenon termed target commitment that reflect...
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| Published in: | Mol Cell Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.13.4302-4310.2001 |
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