RAG Transposase Can Capture and Commit to Target DNA before or after Donor Cleavage

The discovery that the V(D)J recombinase functions as a transposase in vitro suggests that transposition by this system might be a potent source of genomic instability. To gain insight into the mechanisms that regulate transposition, we investigated a phenomenon termed target commitment that reflect...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Neiditch, Matthew B., Lee, Gregory S., Landree, Mark A., Roth, David B.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2001
Assuntos:	DNA Dynamics and Chromosome Structure
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.13.4302-4310.2001
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