Functional Organization of Single and Paired V(D)J Cleavage Complexes
RAG-1 and RAG-2 initiate V(D)J recombination by binding to specific recognition sequences (RSS) and then cleave the DNA in two steps: nicking and hairpin formation. Recent work has established that a dimer of RAG-1 and either one or two monomers of RAG-2 bind to a single RSS, but the enzymatic contr...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87086/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390654/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.13.4256-4264.2001 |
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