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The C-terminal portion of RAG2 protects against transposition in vitro

The assembly of antigen receptor genes by V(D)J recombination is initiated by the RAG1/RAG2 protein complex, which introduces double-strand breaks between recombination signal sequences and their coding DNA. Truncated forms of RAG1 and RAG2 are functional in vivo and have been used to study V(D)J cl...

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Bibliografische gegevens
Hoofdauteurs: Elkin, Sheryl K., Matthews, Adam G., Oettinger, Marjorie A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154476/
https://ncbi.nlm.nih.gov/pubmed/12682025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg184
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