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The C-terminal portion of RAG2 protects against transposition in vitro

The assembly of antigen receptor genes by V(D)J recombination is initiated by the RAG1/RAG2 protein complex, which introduces double-strand breaks between recombination signal sequences and their coding DNA. Truncated forms of RAG1 and RAG2 are functional in vivo and have been used to study V(D)J cl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Elkin, Sheryl K., Matthews, Adam G., Oettinger, Marjorie A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC154476/
https://ncbi.nlm.nih.gov/pubmed/12682025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg184
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