The C-terminal portion of RAG2 protects against transposition in vitro
The assembly of antigen receptor genes by V(D)J recombination is initiated by the RAG1/RAG2 protein complex, which introduces double-strand breaks between recombination signal sequences and their coding DNA. Truncated forms of RAG1 and RAG2 are functional in vivo and have been used to study V(D)J cl...
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| Vydáno v: | EMBO J |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12682025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg184 |
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