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The C-terminal portion of RAG2 protects against transposition in vitro

The assembly of antigen receptor genes by V(D)J recombination is initiated by the RAG1/RAG2 protein complex, which introduces double-strand breaks between recombination signal sequences and their coding DNA. Truncated forms of RAG1 and RAG2 are functional in vivo and have been used to study V(D)J cl...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Elkin, Sheryl K., Matthews, Adam G., Oettinger, Marjorie A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154476/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12682025/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg184
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