The C-terminal portion of RAG2 protects against transposition in vitro

The assembly of antigen receptor genes by V(D)J recombination is initiated by the RAG1/RAG2 protein complex, which introduces double-strand breaks between recombination signal sequences and their coding DNA. Truncated forms of RAG1 and RAG2 are functional in vivo and have been used to study V(D)J cl...

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Опубликовано в::	EMBO J
Главные авторы:	Elkin, Sheryl K., Matthews, Adam G., Oettinger, Marjorie A.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Publishing Group 2003
Предметы:	Articles
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12682025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg184
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