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The C-terminal portion of RAG2 protects against transposition in vitro
The assembly of antigen receptor genes by V(D)J recombination is initiated by the RAG1/RAG2 protein complex, which introduces double-strand breaks between recombination signal sequences and their coding DNA. Truncated forms of RAG1 and RAG2 are functional in vivo and have been used to study V(D)J cl...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC154476/ https://ncbi.nlm.nih.gov/pubmed/12682025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg184 |
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