DNA mismatches and GC-rich motifs target transposition by the RAG1/RAG2 transposase
In addition to their essential role in V(D)J recombination, the RAG proteins function as a transposase capable of inserting the V(D)J recombination intermediate, the signal end DNA fragment, into target DNA. RAG-mediated transposition has been suggested to contribute to genome instability and the de...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275461/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576304/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg819 |
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