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Recruitment of RAG1 and RAG2 to Chromatinized DNA during V(D)J Recombination

V(D)J recombination is initiated by the binding of the RAG1 and RAG2 proteins to recombination signal sequences (RSSs) that consist of conserved heptamer and nonamer sequences separated by a spacer of either 12 or 23 bp. Here, we used RAG-inducible pro-B v-Abl cell lines in conjunction with chromati...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Shetty, Keerthi, Schatz, David G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589606/
https://ncbi.nlm.nih.gov/pubmed/26303526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00219-15
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